EP13: Minimizing Risks Along the Journey: 10 Activities to Prevent Thrombosis While Travelling

Although the likelihood of developing thrombosis on flights exceeding four hours is relatively low—about 1 in 6,000—certain factors such as age, obesity, or recent surgery can increase susceptibility. Fortunately, these 10 practical tips can help minimize the risk while travelling

Minimizing Risks Along the Journey: 10 Activities to Prevent Thrombosis While Travelling 

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Although the likelihood of developing thrombosis on flights exceeding four hours is relatively low—about 1 in 6,000—certain factors such as age, obesity, or recent surgery can increase susceptibility. Fortunately, these 10 practical tips can help minimize the risk while travelling.

1. Before You Travel

Take a 30-minute walk before boarding the plane. If you have a history of blood clots or known risk factors, consult your physician before flying. If you're on anticoagulants, consider wearing a medical alert bracelet or necklace while travelling.

2. Stand up and Walk Regularly

Whether flying, driving, or on a train, aim to stand and walk every 1–2 hours. Movement boosts leg circulation. On planes, walk the aisle when it's safe; during road trips, plan stops to stretch.

3. Do Seated Leg Exercises

If standing isn’t possible, keep your legs active with simple movements like toe lifts, heel raises, and ankle circles. These simple exercises engage your calf muscles, which are essential for promoting venous return.

4. Avoid Crossing Your Legs

Crossing your legs or tucking them under your seat can restrict circulation. Instead, keep your feet flat on the floor and shift your position regularly to promote circulation. 

5. Pick an Aisle Seat

Plasma exchange remains the cornerstone of TTP treatment, serving both to remove autoantibodies and replenish ADAMTS13. Adjunctive therapies include corticosteroids and rituximab, targeting the autoimmune component. Emerging treatments such as caplacizumab and recombinant ADAMTS13 (for the congenital forms) show promise in refractory cases.

6. Wear Comfortable Clothing

Tight clothing, especially around the waist and legs, can impede blood flow. Opt for loose, comfortable attire to reduce constriction and support healthy circulation. 

7. Avoid Sleeping too Long Without Moving

While it’s tempting to sleep through a long flight, try to wake up periodically to stretch or walk. Set a reminder if needed and avoid sleep aids unless prescribed.

8. Stay Hydrated

Dehydration thickens blood, making clots more likely. Drink plenty of water before and during your journey. Limit alcohol and caffeine, as both can contribute to dehydration—especially in the dry air of airplane cabins.

9. Use Compression Stockings if Advised

If you're at higher risk—due to recent surgery, pregnancy, or a history of thrombosis—medical-grade compression stockings may help. Consult your Healthcare provider to see if they’re right for you.

10. After You Arrive

Most travelers won’t experience issues, but if you notice swelling, pain in one leg, or difficulty breathing, seek immediate medical attention or visit the nearest emergency department.

Key Messages

• The risk of developing thrombosis on flights over four hours is relatively low. 
• If you have history of clotting or known risk factors, consult your doctor before travelling. 
• Stand and walk every 1–2 hours during travel. If you can’t, do seated leg exercises to keep blood flowing.
• Stay hydrated by drinking water and limiting alcohol/caffeine.
• If you notice leg swelling, pain, or breathing issues after arrival, seek immediate medical attention.